Vicodin vs. Norco: How Are They Different?

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Last updated: 11/27/2024

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Last Updated - 11/27/2024

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Norco and Vicodin are prescription medications used to manage moderate to severe pain. Both contain hydrocodone, a powerful opioid, and acetaminophen (commonly known as Tylenol). While these brand names are no longer available, their generic versions are widely prescribed under names like hydrocodone/acetaminophen or hydrocodone/APAP. However, due to their potential for addiction and liver damage, it’s crucial to understand their use and risks.

What Is Hydrocodone Used For?

Hydrocodone is an opioid medication primarily prescribed to treat:

  • Severe acute pain, often post-surgery or injury
  • Chronic, long-term pain
  • Persistent cough

Hydrocodone works by altering how the brain perceives pain, mimicking the effects of natural endorphins. It also suppresses cough reflexes by acting on the brain’s cough center. Various medications, such as Hysingla and Zohydro, contain hydrocodone either alone or in combination with other ingredients like acetaminophen.

Overview of Norco

Norco was a combination pain reliever containing hydrocodone and acetaminophen. Though the branded version is discontinued, it’s still available generically in various dosages:

  • Norco 2.5/325: 2.5 mg hydrocodone and 325 mg acetaminophen
  • Norco 5/325: 5 mg hydrocodone and 325 mg acetaminophen
  • Norco 7.5/325: 7.5 mg hydrocodone and 325 mg acetaminophen
  • Norco 10/325: 10 mg hydrocodone and 325 mg acetaminophen

These generic tablets can vary in appearance depending on their manufacturer.

Overview of Vicodin

Vicodin, another hydrocodone-acetaminophen combination, was once available in various strengths (like Vicodin ES and Vicodin HP). Due to FDA guidelines limiting acetaminophen content to 300 mg per dose to prevent liver damage, the original formulations were discontinued. The generic equivalents of Vicodin are still in use, available as:

  • Vicodin 5/300: 5 mg hydrocodone and 300 mg acetaminophen
  • Vicodin ES 7.5/300: 7.5 mg hydrocodone and 300 mg acetaminophen
  • Vicodin HP 10/300: 10 mg hydrocodone and 300 mg acetaminophen

These generics also come in tablet form, with variations in shape and markings.

Side Effects of Norco and Vicodin

Both Norco and Vicodin generics share similar side effects, mainly due to the hydrocodone component. Common side effects include:

  • Constipation
  • Drowsiness
  • Dry mouth
  • Lightheadedness
  • Mood changes
  • Rash or itching

Severe side effects or overdose symptoms may involve:

  • Slow or irregular breathing
  • Hallucinations or severe confusion
  • Nausea, vomiting, or abdominal pain
  • Signs of liver damage, such as jaundice or fatigue

The acetaminophen component can be particularly harmful in large doses, leading to liver toxicity.

Comparing Norco and Vicodin

The key difference between Norco and Vicodin generics is the acetaminophen content—325 mg in Norco versus 300 mg in Vicodin. For individuals with liver concerns or those taking other acetaminophen-containing medications, this difference might be significant. Both medications are effective at pain relief, but they should be used cautiously due to the risk of tolerance, dependence, and addiction.

Risk of Addiction

Hydrocodone is a highly addictive substance, especially when misused. In 2020, around 9.3 million Americans misused prescription opioids, including hydrocodone-based drugs like Norco and Vicodin. Misuse can lead to addiction, characterized by behaviors such as:

  • Continuing use despite negative consequences
  • Cravings and inability to reduce usage
  • Increased tolerance, requiring higher doses for the same effect
  • Withdrawal symptoms when stopping the drug

Treatment for Hydrocodone Addiction

For those struggling with hydrocodone addiction, various treatment options are available to support recovery. Treatment plans are personalized and may include:

  • Medical Detox: Supervised detox to manage withdrawal symptoms safely.
  • Inpatient Rehab: Intensive support in a structured environment.
  • Outpatient Programs: Flexible care allowing individuals to continue daily responsibilities.
  • Teletherapy: Online counseling for convenient, ongoing support.

At The Recovery Village Indianapolis, our specialized team can guide you through a personalized treatment plan. If you or a loved one is facing addiction, reach out to us for comprehensive support on the road to recovery.

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