Hydrocodone Overdose: How Much Is Too Much?
Written by The Recovery Village Indianapolis
& Medically Reviewed by Dr. Kevin Wandler, MD
Medically Reviewed
Last updated: 12/03/2024
Hydrocodone is a prescription opioid commonly used to manage pain. Like other opioids, it works by slowing and suppressing normal brain signaling, effectively dulling pain sensations. However, when taken in excessive doses, hydrocodone can dangerously slow or stop breathing, leading to overdose or even death.
If you or someone you care about is taking hydrocodone, it is crucial to understand the potential for overdose, recognize the symptoms, and know how to respond in an emergency.
How Much Hydrocodone Can Cause an Overdose?
The threshold for a hydrocodone overdose varies depending on individual factors such as body weight, tolerance, and health conditions. Generally, doses of 50 mg or higher significantly increase the risk of overdose, while doses of 90 mg or more are considered extremely high-risk. Most medical professionals would never prescribe doses this large.
The risk of overdose is even greater when hydrocodone is combined with other depressants, such as alcohol, benzodiazepines, or other opioids. These substances amplify each other’s sedative effects, heightening the likelihood of a fatal overdose.
Risks of Acetaminophen in Hydrocodone
Hydrocodone is often combined with acetaminophen, a common pain reliever found in over-the-counter medications like Tylenol. This combination increases the drug’s effectiveness against pain but also introduces additional risks.
Risks of Acetaminophen:
- Short-Term: High doses can cause severe liver damage.
- Long-Term: Chronic use of hydrocodone with acetaminophen increases the likelihood of liver toxicity.
Healthy adults should not exceed 1 gram of acetaminophen in a six-hour period or 4 grams in a single day. Since acetaminophen is included in many medications, it’s important to account for all sources to avoid unintentional overdose.
Symptoms of a Hydrocodone Overdose
During an overdose, the affected individual is often unable to help themselves. Therefore, it is critical for those around them to recognize the signs and act quickly. Symptoms of a hydrocodone overdose include:
- Physical Signs: Small pupils, pale or clammy skin, blue lips or nails
- Behavioral Symptoms: Drowsiness, unresponsiveness, confusion
- Breathing Issues: Slow, shallow, or absent breathing
- Other Indicators: Vomiting, abdominal pain, fainting
If someone displays any of these symptoms, especially breathing difficulties, immediate medical intervention is required to prevent severe complications or death.
The Growing Impact of Hydrocodone Overdose Deaths
In 2021, overdose deaths in the United States surpassed 100,000 annually, with opioids responsible for over 75% of these fatalities. Although hydrocodone-specific data is not always separated, opioids as a drug class account for the highest overdose death rates.
Common Causes of Hydrocodone Overdose
Hydrocodone overdose can occur in various situations, including:
- Accidental Misuse: This may happen if a child accesses improperly stored medication, if a dose is mistakenly repeated, or if medication instructions are misunderstood.
- Substance Abuse: Individuals addicted to hydrocodone may take excessive doses to achieve stronger effects. Abuse can involve taking hydrocodone more frequently than prescribed or using it in unintended ways, such as crushing pills to inhale or inject them.
What to Do in a Suspected Overdose
If you suspect someone is experiencing a hydrocodone overdose, acting swiftly can save their life. Follow these steps:
- Administer Naloxone (Narcan): This medication can temporarily reverse the effects of hydrocodone, buying critical time to seek further treatment.
- Call 911: Emergency services can provide instructions and dispatch help quickly.
- Monitor Breathing: Watch for slow or absent breathing. If necessary, perform CPR until professional help arrives.
- Position Safely: If the person is breathing independently, place them on their side to reduce the risk of choking on vomit or saliva.
Hydrocodone Overdose Treatment
Naloxone (Narcan) is an effective first-line response to opioid overdoses. However, its effects are short-lived, and symptoms can return after the medication wears off. In a medical setting, naloxone can be administered continuously to counteract hydrocodone’s effects, particularly in cases involving extended-release formulations that can last 12 hours or more.
When acetaminophen is involved in the overdose, additional treatments are required to minimize liver damage. In severe cases, a liver transplant may be necessary.
Preventing Hydrocodone Overdose and Finding Support
No one anticipates experiencing a hydrocodone overdose, but addiction often drives people to take risks they wouldn’t normally consider. If you or a loved one is struggling with opioid addiction, the only surefire way to avoid overdose is to stop using hydrocodone and other opioids entirely.
Breaking free from opioid addiction is challenging, but it is possible with the right support. At The Recovery Village Indianapolis, we offer evidence-based treatment programs in a state-of-the-art facility to help individuals safely and effectively recover from opioid addiction. Our approach includes:
- Medical Detox: Supervised care to manage withdrawal symptoms safely.
- Inpatient Rehab: Structured programs tailored to individual needs.
- Therapies and Counseling: Addressing the root causes of addiction and building coping skills for long-term recovery.
If you or someone you know is struggling with hydrocodone addiction, don’t wait for a crisis. Contact The Recovery Village Indianapolis today to begin your journey to a healthier, addiction-free life.
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