How Long Does Ativan (Lorazepam) Stay in Your System?

Ativan (lorazepam), a benzodiazepine commonly prescribed to treat anxiety, is a habit-forming substance that takes about 60 hours to clear from the body. This timeline can vary depending on several factors. Here’s an overview of how Ativan works, its elimination process, and considerations regarding its potential for abuse.

Ativan’s Half-Life and Elimination

• Half-Life: Ativan has a half-life of approximately 12 hours, meaning half of a single dose is metabolized within that time frame.
• Full Clearance: It generally takes five half-lives—around 60 hours—for a dose of Ativan to be completely eliminated.
• Metabolites: The liver breaks down Ativan into metabolites, with a primary breakdown product having a half-life of 18 hours. This metabolite may linger in the body for about 90 hours.
• Drug Interactions: Certain medications, like Probenecid (used for gout), can extend Ativan’s half-life, while others, such as Theophylline (for asthma), may shorten it.

Factors Affecting Ativan Elimination

• Dosage: Higher doses take longer for the body to process.
• Frequency of Use: Repeated or long-term use extends the elimination timeline.
• Method of Administration: Ativan taken orally versus by injection may clear at different rates.
• Age: Older adults metabolize Ativan about 20% slower than younger individuals.

Ativan Drug Testing

Detection windows for Ativan vary based on the type of test used:

• Urine: Detectable two hours post-use, with traces remaining for three to six days.
• Blood: Peaks within one to six hours and may remain detectable for several days.
• Hair: Rarely shows up in hair tests and, when it does, appears in minimal concentrations.
• Saliva: Can be found 15 minutes after use and lasts around eight hours.

False positives are possible, with medications like efavirenz (HIV), sertraline (mood disorders), and oxaprozin (pain relief) potentially mimicking benzodiazepines on tests.

FAQs About Ativan

What Is Ativan Used For?
Ativan was approved in 1977 to treat anxiety, with later approval for injectable use in seizures and pre-anesthesia.

Is Ativan Addictive?
As a Schedule IV controlled substance, Ativan carries a risk of misuse and dependence. It is recommended for short-term use, typically up to four weeks. Abrupt discontinuation may result in withdrawal symptoms.

What Are the Signs of Ativan Addiction?
Indicators of addiction include:

• Needing higher doses for the same effect
• Persistent misuse despite negative consequences
• Failed attempts to stop using Ativan
• Prioritizing Ativan over relationships and responsibilities
• Recreational buying or selling of the drug

Seeking Help for Ativan Dependence

If you or someone you love is struggling with Ativan misuse, professional help is available. Recovery involves personalized treatment and support to overcome dependence safely and effectively. Don’t wait—start your journey to recovery and call today.