Can I Mix DXM (Dextromethorphan) and Alcohol?
Written by The Recovery Village Indianapolis
& Medically Reviewed by Dr. Kevin Wandler, MD
Medically Reviewed
Last updated: 11/14/2024
Risks of Mixing DXM and Alcohol
Dextromethorphan (DXM) is a common ingredient in many over-the-counter cough medicines. While it is effective for suppressing coughs, combining DXM with alcohol can lead to dangerous interactions. These two substances affect the central nervous system and can increase the risk of side effects, making it crucial to understand the risks before consuming them together.
What Is DXM?
DXM, or dextromethorphan, is widely used in cough, cold, and flu medications. Since its approval by the FDA in 1958, it has become one of the most frequently used ingredients for treating coughs. The exact way DXM suppresses the cough reflex is not entirely understood, but it is known to interact with receptors in the brain, although not the same ones targeted by opioids. Despite not being a traditional opioid, DXM is structurally similar and can be misused for its psychoactive effects. An estimated 1.5 million Americans misuse DXM-containing cough medications to achieve a high.
Common Side Effects of DXM
When taken according to label instructions, DXM is generally safe. However, some individuals may experience mild side effects, such as:
- Nausea
- Stomach upset
- Drowsiness
- Dizziness
High doses taken for recreational purposes, also known as “Robo-tripping,” can lead to more severe effects, including:
- Confusion and paranoia
- Over-excitability and agitation
- Hallucinations
- Slurred speech and coordination issues
- Elevated blood pressure
- Sensory distortions (e.g., feeling like floating)
- Eye spasms
- Euphoria and altered mood
In extreme cases, an overdose can be life-threatening, especially when combined with other substances like alcohol. Immediate medical attention is required if you suspect someone has overdosed on DXM.
Signs of DXM Misuse
Misusing DXM is often marked by behaviors such as:
- Taking DXM in higher-than-recommended doses
- Using DXM without a medical reason
- Mixing DXM with alcohol or other drugs
- Exhibiting cravings for DXM
- Displaying the high-dose side effects listed above
While DXM misuse on its own is rarely fatal, combining it with other substances, including alcohol, can significantly increase the risk of serious, potentially deadly side effects.
The Dangers of Mixing DXM and Alcohol
Both DXM and alcohol are central nervous system depressants. When taken together, their effects can be amplified, leading to:
- Severe dizziness and drowsiness
- Impaired judgment and concentration
- Problems with coordination and thinking clearly
In addition to these effects, combining DXM and alcohol increases the risk of a fatal overdose. The dangers vary depending on how much of each substance is consumed. Some people intentionally mix DXM with alcohol to intensify their high, a practice known as “Robotripping,” “dexing,” or “skittling.” This can lead to emergency room visits, with about 6,000 cases annually linked to DXM mixed with substances like alcohol, antihistamines, and other over-the-counter drugs.
Moreover, taking alcohol while using DXM—often when you’re already sick—can weaken your immune system, prolong your illness, and worsen your symptoms.
How Long Should You Wait to Drink After Taking DXM?
If you’re using DXM to treat a cough or cold, it’s advisable to avoid alcohol entirely until you’re fully recovered. Alcohol suppresses the immune system, which can extend the duration of your illness.
The half-life of DXM, which is the time it takes for half the drug to leave your system, varies significantly. It can range from as short as 2.4 hours to as long as 19 hours based on individual metabolism and other factors. Given that it takes about five half-lives for a drug to be completely cleared from your body, DXM can linger for up to four days. To avoid adverse effects, consult with a healthcare professional before consuming alcohol after taking DXM.
Treatment for DXM and Alcohol Misuse
Struggling with the misuse of DXM and alcohol can be challenging, but recovery is possible. The Recovery Village Indianapolis offers a range of treatment options for those dealing with substance use disorders, including:
- Medical Detox: Our medical team provides 24/7 care to help you safely detox from substances like DXM and alcohol.
- Inpatient Rehab: A structured, supportive environment to help you focus on recovery.
- Intensive Outpatient Programs (IOP): Flexible treatment options that allow you to continue with daily responsibilities while receiving therapy.
- Partial Hospitalization Programs (PHP): A step-down from inpatient care, offering intensive treatment without overnight stays.
- Aftercare Support: Continued support to help maintain long-term sobriety.
If you or a loved one is struggling with the misuse of DXM and alcohol, don’t hesitate to reach out. The Recovery Village Indianapolis is here to provide compassionate care and evidence-based treatment to guide you on the path to recovery. Contact us today to take the first step toward a healthier, substance-free life.
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